Experimental Cryptococcosis in Mice
نویسندگان
چکیده
منابع مشابه
Specific and Non-specific Immunity in Experimental Cryptococcosis in Mice
The course of lethal cryptococcosis in mice was modified by immunization with the same strain or different strains of Cryptococcus neoformans. Protection was associated with a definite decrease in tissue fungus multiplication over the initial 7 days of infection. Such immunity was species-specific and did not protect against heterologous challenge with Staphylococcus aureus, Klebsiella pneumoni...
متن کاملExperimental cryptococcosis in normal and T cell deficient mice.
B-cell-deficient mice were prepared by administration of rabbit anti-mouse-mu antiserum to newborn animals within 12 h of birth onwards. Such immunodeficient animals, along with the normal controls, were infected intravenously with Cryptococcus neoformans. There was no difference in the mortality pattern, viable count of cryptococci in different organs, delayed-type hypersensitivity reaction, a...
متن کاملExperimental ocular cryptococcosis. Preliminary studies in cats and mice.
Ocular cryptococcosis was produced in cats by the intracarotid injection of Cryptococcus neoformans. Infected eyes developed a progressive, multifocal chorioretinitis which was comparable to that found in the naturally occurring feline disease. The severity of the ocular disease, the development of infection in the fellow eye, and the degree of systemic involvement were shown to be related to t...
متن کاملExperimental Models of Cryptococcosis
Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction. Here we review the range of experimental ...
متن کاملFurther Studies on Immunity in Experimental Cryptococcosis
Following infection with 10(3) cells of Cryptococcus neoformans, progressive multiplication occurred in all tissues for 7 to 28 days. Thereafter, most mice gained control of the infection so that 3 to 6 months after inoculation, tissues were usually sterile or contained only small numbers of cryptococci. Survivors challenged 1 to 4 months after infection with 10(3) cells lived longer than contr...
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ژورنال
عنوان ژورنال: Japanese Journal of Medical Mycology
سال: 1974
ISSN: 1884-6971,0583-0516
DOI: 10.3314/jjmm1960.15.52